Product name | Carvedilol |
Appearance | white crystalline powder,odourless |
Solubility | soluble in glacial acetic acid;Soluble in chloroform;Slightly soluble in methanol ethyl acetate;Practically insoluble in water. |
Melting point | 114.0~118.0ºC |
Identification | λmax=285nm,319nm,331nm±2nm |
0.4-0.44(the absorbance ratio of 331nm and 285nm) |
Infrared absorption spectrum should be consistent with the reference substance |
Clarity and color of acetic acid solution | clear and colorless ,Max. Standard yellow |
Singel color solution | ≤0.2% |
Total impurities | ≤0.5% |
Loss on drying | ≤0.5% |
Residue on ignition | ≤0.1% |
function | Carvedilol has strong heart and neuroprotective effects: unlike normal β-receptor antagonists, long-term use of this product in hypertensive patients can not only dilate coronary and renal vessels, reduce peripheral vascular resistance, but also reduce systemic circulation. And pulmonary circulation resistance, effectively control high blood pressure. This product has a protective effect on renal function, does not change renal blood flow, but reduces microalbuminuria, reduces renal vascular resistance, and has a good regulatory effect on blood lipids. |